Redox Status Is Critical for Stemness in Skin Equivalents
نویسندگان
چکیده
منابع مشابه
Redox Status Is Critical for Stemness in Skin Equivalents
The skin is constantly exposed to environmental oxidative stress. Skin equivalent (SE) models are three-dimensional systems in which cell-cell or cell-matrix interactions can be investigated. In this study, the effects of vitamin C or plant extracts with high antioxidant activities were tested. There was no significant difference in the epidermal thickness, but the basal cells became cuboidal w...
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In this study we investigated the effects of fucoidan on the proliferation of fibroblasts and the reconstruction of a skin equivalent (SE). Fucoidan significantly stimulated the proliferation of CCD-25Sk human fibroblasts and Western blot analysis demonstrated that fucoidan markedly increased the expression of cyclin D1 and decreased the expression of p27. Fucoidan was used to reconstruct SE. I...
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ژورنال
عنوان ژورنال: Oxidative Medicine and Cellular Longevity
سال: 2012
ISSN: 1942-0900,1942-0994
DOI: 10.1155/2012/819623